Melissa Kotterman

Melissa Kotterman

Company: 4D Molecular Therapeutics

Job title: VP, Discovery & Engineering, Co-Founder


Improving AAV Capsids Using Directed Evolution 2:30 pm

Current AAV serotypes have relatively modest tissue selectivity. Not all tissue types can be effectively transduced Directed Evolution can dramatically enhance AAV preference and lead to effective transduction of otherwise unavailable tissue types Promoter engineering can further enhance specificity These “Next Generation” vectors have the potential to broaden the effective and safe use of gene…Read more

day: Track B - Day 1 pm

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